Engineering Parvalbumin for the Heart: Optimizing the Mg(2+) Binding Properties of Rat β-Parvalbumin

Parvalbumin (PV), an EF-hand protein family member, is a delayed calcium buffer that exchanges magnesium for calcium to facilitate fast skeletal muscle relaxation. Genetic approaches that express parvalbumin in the heart also enhance relaxation and show promise of being therapeutic against various c...

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Detalles Bibliográficos
Autores principales: Zhang, Jianchao, Shettigar, Vikram, Zhang, George C., Kindell, Daniel G., Liu, Xiaotong, López, Joseph J., Yerrimuni, Vinatham, Davis, Grace A., Davis, Jonathan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204457/
https://www.ncbi.nlm.nih.gov/pubmed/22059076
http://dx.doi.org/10.3389/fphys.2011.00077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204457/
https://www.ncbi.nlm.nih.gov/pubmed/22059076
http://dx.doi.org/10.3389/fphys.2011.00077

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