N-Methyl-N'-nitro-N-nitrosoguanidine-induced senescence-like growth arrest in colon cancer cells is associated with loss of adenomatous polyposis coli protein, microtubule organization, and telomeric DNA

BACKGROUND: Cellular senescence is a state in which mammalian cells enter into an irreversible growth arrest and altered biological functions. The senescence response in mammalian cells can be elicited by DNA-damaging agents. In the present study we report that the DNA-damaging agent N-methyl-N'...

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Detalles Bibliográficos
Autores principales: Jaiswal, Aruna S, Multani, Asha S, Pathak, Sen, Narayan, Satya
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC320492/
https://www.ncbi.nlm.nih.gov/pubmed/14728717
http://dx.doi.org/10.1186/1476-4598-3-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC320492/
https://www.ncbi.nlm.nih.gov/pubmed/14728717
http://dx.doi.org/10.1186/1476-4598-3-3

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