Cargando…

Effects of Dietary Fish Oil on the Depletion of Carcinogenic PAH-DNA Adduct Levels in the Liver of B6C3F1 Mouse

Many carcinogenic polycyclic aromatic hydrocarbons (PAHs) and their metabolites can bind covalently to DNA. Carcinogen-DNA adducts may lead to mutations in critical genes, eventually leading to cancer. In this study we report that fish oil (FO) blocks the formation of DNA adducts by detoxification o...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Guo-Dong, Zhu, Huiping, Phillips, Tracie D., Wang, Jianbo, Wang, Shi-Zhou, Wang, Fen, Amendt, Brad A., Couroucli, Xanthi I., Donnelly, Kirby C., Moorthy, Bhagavatula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204992/
https://www.ncbi.nlm.nih.gov/pubmed/22066002
http://dx.doi.org/10.1371/journal.pone.0026589