Cargando…

Effects of Dietary Fish Oil on the Depletion of Carcinogenic PAH-DNA Adduct Levels in the Liver of B6C3F1 Mouse

Many carcinogenic polycyclic aromatic hydrocarbons (PAHs) and their metabolites can bind covalently to DNA. Carcinogen-DNA adducts may lead to mutations in critical genes, eventually leading to cancer. In this study we report that fish oil (FO) blocks the formation of DNA adducts by detoxification o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Guo-Dong, Zhu, Huiping, Phillips, Tracie D., Wang, Jianbo, Wang, Shi-Zhou, Wang, Fen, Amendt, Brad A., Couroucli, Xanthi I., Donnelly, Kirby C., Moorthy, Bhagavatula
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204992/ https://www.ncbi.nlm.nih.gov/pubmed/22066002 http://dx.doi.org/10.1371/journal.pone.0026589

Ejemplares similares

Analysis of the Transcriptome in Hyperoxic Lung Injury and Sex-Specific Alterations in Gene Expression
por: Lingappan, Krithika, et al.
Publicado: (2014)

Role of Cytochrome P450 (CYP)1A in Hyperoxic Lung Injury: Analysis of the Transcriptome and Proteome
por: Lingappan, Krithika, et al.
Publicado: (2017)

Attenuation of Polycyclic Aromatic Hydrocarbon (PAH)-Mediated Pulmonary DNA Adducts and Cytochrome P450 (CYP)1B1 by Dietary Antioxidants, Omega-3 Fatty Acids, in Mice
por: Zhou, Guodong, et al.
Publicado: (2022)

Role of Human NADPH Quinone Oxidoreductase (NQO1) in Oxygen-Mediated Cellular Injury and Oxidative DNA Damage in Human Pulmonary Cells
por: Burke, Rebecca, et al.
Publicado: (2021)

Carcinogen adducts as an indicator for the public health risks of consuming carcinogen-exposed fish and shellfish.
por: Dunn, B P
Publicado: (1991)

Polycyclic aromatic hydrocarbons and PAH-related DNA adducts
por: Ewa, Błaszczyk, et al.
Publicado: (2016)

DNA adducts in human tissues: biomarkers of exposure to carcinogens in tobacco smoke.
por: Phillips, D H
Publicado: (1996)

Postlabeling methods for carcinogen-DNA adduct analysis.
por: Randerath, K, et al.
Publicado: (1985)

Polycyclic Aromatic Hydrocarbon (PAH) Exposure and DNA Adduct Semi-Quantitation in Archived Human Tissues
por: Pratt, M. Margaret, et al.
Publicado: (2011)

DNA adducts and carcinogenicity of nitro-polycyclic aromatic hydrocarbons.
por: Fu, P P, et al.
Publicado: (1994)

PAH–DNA Adducts, Cigarette Smoking, GST Polymorphisms, and Breast Cancer Risk
por: McCarty, Kathleen M., et al.
Publicado: (2009)

DNA adducts and related biomarkers in populations exposed to environmental carcinogens
por: Perera, Frederica, et al.
Publicado: (1992)

Formation and Repair of Tobacco Carcinogen-Derived Bulky DNA Adducts
por: Hang, Bo
Publicado: (2010)

Carcinogenic adducts induce distinct DNA polymerase binding orientations
por: Vrtis, Kyle B., et al.
Publicado: (2013)

PAH–DNA Adducts in Cord Blood and Fetal and Child Development in a Chinese Cohort
por: Tang, Deliang, et al.
Publicado: (2006)

Key Factors for Improving the Carcinogenic Risk Assessment of PAH Inhalation Exposure by Monte Carlo Simulation
por: Qin, Ning, et al.
Publicado: (2021)

Association of PAH-DNA adducts in peripheral white blood cells with dietary exposure to polyaromatic hydrocarbons.
por: Rothman, N, et al.
Publicado: (1993)

Pollution Sources and Carcinogenic Risk of PAHs in PM(1) Particle Fraction in an Urban Area
por: Jakovljević, Ivana, et al.
Publicado: (2020)

The carcinogenicity of methoxyl derivatives of 4-aminoazobenzene: correlation between DNA adducts and genotoxicity.
por: Kojima, M, et al.
Publicado: (1994)

DNA adduct measurements and tumor incidence during chronic carcinogen exposure in rodents.
por: Poirier, M C, et al.
Publicado: (1994)

Cytotoxic and mutagenic effects of specific carcinogen-DNA adducts in diploid human fibroblasts.
por: McCormick, J J, et al.
Publicado: (1985)

Carcinogen-DNA adducts in exfoliated urothelial cells: techniques for noninvasive human monitoring.
por: Talaska, G, et al.
Publicado: (1993)

DNA Polymerase: Structural Homology, Conformational Dynamics, and the Effects of Carcinogenic DNA Adducts
por: Federley, Richard G., et al.
Publicado: (2010)

Carcinogen-induced depletion of cutaneous Langerhans cells.
por: Muller, H. K., et al.
Publicado: (1985)

Carcinogens and cancers in freshwater fishes.
por: Black, J J, et al.
Publicado: (1991)

Formation Mechanism of Benzo(a)pyrene: One of the Most Carcinogenic Polycyclic Aromatic Hydrocarbons (PAH)
por: Reizer, Edina, et al.
Publicado: (2019)

Detection of carcinogen-DNA adducts in human fetal tissues by the 32P-postlabeling procedure.
por: Hansen, C, et al.
Publicado: (1993)

Infection with carcinogenic helminth parasites and its production of metabolites induces the formation of DNA-adducts
por: Gouveia, Maria João, et al.
Publicado: (2019)

Carcinogenic Activity and Risk Assessment of PAHs in Ambient Air: PM(10) Particle Fraction and Bulk Deposition
por: Jakovljević, Ivana, et al.
Publicado: (2023)

Impacts of PAH accumulation on reproductive hormones, indices of oxidative stress and BPDE-albumin adduct in women with recurrent pregnancy loss
por: El-Sikaily, Amany, et al.
Publicado: (2023)

Oncozoons and the search for carcinogen-indicator fishes.
por: Dawe, C J
Publicado: (1987)

DNA adduct formation in the human nasal mucosa as a biomarker of exposure to environmental mutagens and carcinogens.
por: Flato, S, et al.
Publicado: (1996)

The use of an artificial nucleotide for polymerase-based recognition of carcinogenic O(6)-alkylguanine DNA adducts
por: Wyss, Laura A., et al.
Publicado: (2016)

Future directions in the use of DNA adducts as internal dosimeters for monitoring human exposure to environmental mutagens and carcinogens.
por: Harris, C C
Publicado: (1985)

Sensitive CometChip assay for screening potentially carcinogenic DNA adducts by trapping DNA repair intermediates
por: Ngo, Le P, et al.
Publicado: (2020)

DNA adducts as link between in vitro and in vivo carcinogenicity – A case study with benzo[a]pyrene
por: Gerhards, Martin, et al.
Publicado: (2022)

Dact2 Represses PITX2 Transcriptional Activation and Cell Proliferation through Wnt/beta-Catenin Signaling during Odontogenesis
por: Li, Xiao, et al.
Publicado: (2013)

Hemodynamics in pulmonary arterial hypertension (PAH): do they explain long-term clinical outcomes with PAH-specific therapy?
por: Steele, Peter, et al.
Publicado: (2010)

Genotoxic mechanisms for the carcinogenicity of the environmental pollutants and carcinogens o-anisidine and 2-nitroanisole follow from adducts generated by their metabolite N-(2-methoxyphenyl)-hydroxylamine with deoxyguanosine in DNA
por: Stiborová, Marie, et al.
Publicado: (2009)

Correlation of Occupational Exposure to Carcinogenic Polycyclic Aromatic Hydrocarbons (cPAHs) and Blood Levels of p53 and p21 Proteins
por: Saleh, Saleh A. K., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_bkpiuhv37e7rjvvlga4hit2r54