Cargando…

Novel formulation of a methotrexate derivative with a lipid nanoemulsion

BACKGROUND: Lipid nanoemulsions that bind to low-density lipoprotein receptors can concentrate chemotherapeutic agents in tissues with low-density lipoprotein receptor overexpression and decrease the toxicity of the treatment. The aim of this study was to develop a new formulation using a lipophilic...

Descripción completa

Detalles Bibliográficos
Autores principales: Moura, Juliana A, Valduga, Claudete J, Tavares, Elaine R, Kretzer, Iara F, Maria, Durvanei A, Maranhão, Raul C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205125/
https://www.ncbi.nlm.nih.gov/pubmed/22072866
http://dx.doi.org/10.2147/IJN.S18039