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Novel formulation of a methotrexate derivative with a lipid nanoemulsion
BACKGROUND: Lipid nanoemulsions that bind to low-density lipoprotein receptors can concentrate chemotherapeutic agents in tissues with low-density lipoprotein receptor overexpression and decrease the toxicity of the treatment. The aim of this study was to develop a new formulation using a lipophilic...
Autores principales: | Moura, Juliana A, Valduga, Claudete J, Tavares, Elaine R, Kretzer, Iara F, Maria, Durvanei A, Maranhão, Raul C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205125/ https://www.ncbi.nlm.nih.gov/pubmed/22072866 http://dx.doi.org/10.2147/IJN.S18039 |
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