Reduction of atherosclerotic lesions in rabbits treated with etoposide associated with cholesterol-rich nanoemulsions

OBJECTIVES: Cholesterol-rich nanoemulsions (LDE) bind to low-density lipoprotein (LDL) receptors and after injection into the bloodstream concentrate in aortas of atherosclerotic rabbits. Association of paclitaxel with LDE markedly reduces the lesions. In previous studies, treatment of refractory ca...

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Detalles Bibliográficos
Autores principales: Tavares, Elaine R, Freitas, Fatima R, Diament, Jayme, Maranhão, Raul C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205126/
https://www.ncbi.nlm.nih.gov/pubmed/22072867
http://dx.doi.org/10.2147/IJN.S24048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205126/
https://www.ncbi.nlm.nih.gov/pubmed/22072867
http://dx.doi.org/10.2147/IJN.S24048

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