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In situ formation of nanocrystals from a self-microemulsifying drug delivery system to enhance oral bioavailability of fenofibrate

OBJECTIVES: In situ formation of nanocrystals and dissolution profiles of fenofibrate (FFB) from a self-microemulsifying drug delivery system (SMEDDS) were characterized. METHODS: SMEDDS formulated with Myritol(®) and surfactant mixture (Smix) of D-α-Tocopheryl polyethylene glycol 1000 succinate (TP...

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Detalles Bibliográficos
Autores principales: Lin, You-Meei, Wu, Jui-Yu, Chen, Ying-Chen, Su, Yu-Der, Ke, Wen-Tin, Ho, Hsiu-O, Sheu, Ming-Thau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205139/
https://www.ncbi.nlm.nih.gov/pubmed/22072880
http://dx.doi.org/10.2147/IJN.S25339