Gas-phase purification enables accurate, large-scale, multiplexed proteome quantification with isobaric tagging

We describe a mass spectrometry method, QuantMode, which improves the accuracy of isobaric tag–based quantification by alleviating the pervasive problem of precursor interference—co-isolation of impurities—through gas-phase purification. QuantMode analysis of a yeast sample ‘contaminated’ with inter...

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Detalles Bibliográficos
Autores principales: Wenger, Craig D, Lee, M Violet, Hebert, Alexander S, McAlister, Graeme C, Phanstiel, Douglas H, Westphall, Michael S, Coon, Joshua J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205195/
https://www.ncbi.nlm.nih.gov/pubmed/21963608
http://dx.doi.org/10.1038/nmeth.1716

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205195/
https://www.ncbi.nlm.nih.gov/pubmed/21963608
http://dx.doi.org/10.1038/nmeth.1716

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