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MS3 eliminates ratio distortion in isobaric labeling-based multiplexed quantitative proteomics
Quantitative mass spectrometry-based proteomics is highly versatile, but not easily multiplexed. Isobaric labeling strategies allow mass spectrometry-based multiplexed proteome quantification; however, ratio distortion due to protein quantification interference is a common effect. We present a multi...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205343/ https://www.ncbi.nlm.nih.gov/pubmed/21963607 http://dx.doi.org/10.1038/nmeth.1714 |