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Direct observation of disulfide isomerization in a single protein
Photochemical uncaging techniques use light to release active molecules from otherwise inert compounds. Here we expand this class of techniques by demonstrating the mechanical uncaging of a reactive species within a single protein. We prove this novel technique by capturing the regiospecific reactio...
Autores principales: | Alegre-Cebollada, Jorge, Kosuri, Pallav, Rivas-Pardo, Jaime Andrés, Fernández, Julio M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205468/ https://www.ncbi.nlm.nih.gov/pubmed/22024885 http://dx.doi.org/10.1038/nchem.1155 |
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