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Fibroblast activation protein is induced by inflammation and degrades type I collagen in thin-cap fibroatheromata
AIMS: Collagen degradation in atherosclerotic plaques with thin fibrous caps renders them more prone to rupture. Fibroblast activation protein (FAP) plays a role in arthritis and tumour formation through its collagenase activity. However, the significance of FAP in thin-cap human fibroatheromata rem...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205479/ https://www.ncbi.nlm.nih.gov/pubmed/21292680 http://dx.doi.org/10.1093/eurheartj/ehq519 |