Fibroblast activation protein is induced by inflammation and degrades type I collagen in thin-cap fibroatheromata

AIMS: Collagen degradation in atherosclerotic plaques with thin fibrous caps renders them more prone to rupture. Fibroblast activation protein (FAP) plays a role in arthritis and tumour formation through its collagenase activity. However, the significance of FAP in thin-cap human fibroatheromata rem...

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Detalles Bibliográficos
Autores principales: Brokopp, Chad E., Schoenauer, Roman, Richards, Peter, Bauer, Stefan, Lohmann, Christine, Emmert, Maximilian Y., Weber, Benedikt, Winnik, Stephan, Aikawa, Elena, Graves, Kirk, Genoni, Michele, Vogt, Peter, Lüscher, Thomas F., Renner, Christoph, Hoerstrup, Simon P., Matter, Christian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205479/
https://www.ncbi.nlm.nih.gov/pubmed/21292680
http://dx.doi.org/10.1093/eurheartj/ehq519

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