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Interleukin-13, but Not Indomethacin, Increases Cysteinyl-Leukotriene Synthesis in Human Lung Macrophages

Aspirin-exacerbated respiratory disease (AERD) is associated with constitutively elevated synthesis of bronchoconstrictor cysteinyl-leukotrienes, associated with increased expression of leukotriene (LT)C(4) synthase and Th2 cytokines and airway eosinophilia. We examined whether interleukin-13 can in...

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Detalles Bibliográficos
Autores principales: Jackson, Sarah E., Holloway, John W., Warner, Jane A., Sampson, Anthony P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205618/
https://www.ncbi.nlm.nih.gov/pubmed/22121385
http://dx.doi.org/10.1155/2012/348741