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Reduced Central Memory CD4+ T Cells and Increased T-Cell Activation Characterise Treatment-Naive Patients Newly Diagnosed at Late Stage of HIV Infection

Objectives. We investigated immune phenotypes of HIV+ patients who present late, considering late presenters (LPs, CD4+ < 350/μL and/or AIDS), advanced HIV disease (AHD, CD4+ < 200/μL and/or AIDS), and AIDS presenters (AIDS-defining condition at presentation, independently from CD4+). Methods....

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Detalles Bibliográficos
Autores principales: Bai, Francesca, Tincati, Camilla, Merlini, Esther, Pacioni, Carlotta, Sinigaglia, Elisabetta, Carpani, Giovanni, d'Arminio Monforte, Antonella, Marchetti, Giulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205670/
https://www.ncbi.nlm.nih.gov/pubmed/22110905
http://dx.doi.org/10.1155/2012/314849