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The Effect of the Thioether-Bridged, Stabilized Angiotensin-(1–7) Analogue Cyclic Ang-(1–7) on Cardiac Remodeling and Endothelial Function in Rats with Myocardial Infarction

Modulation of renin-angiotensin system (RAS) by angiotensin-(1–7) (Ang-(1–7)) is an attractive approach to combat the detrimental consequences of myocardial infarction (MI). However Ang-(1–7) has limited clinical potential due to its unfavorable pharmacokinetic profile. We investigated effects of a...

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Detalles Bibliográficos
Autores principales: Durik, Matej, van Veghel, Richard, Kuipers, Anneke, Rink, Rick, Haas Jimoh Akanbi, Marijke, Moll, Gert, Danser, A. H. Jan, Roks, Anton J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205684/
https://www.ncbi.nlm.nih.gov/pubmed/22121478
http://dx.doi.org/10.1155/2012/536426