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Nuclear localization of γ-tubulin affects E2F transcriptional activity and S-phase progression

We show that the centrosome- and microtubule-regulating protein γ-tubulin interacts with E2 promoter binding factors (E2Fs) to modulate E2F transcriptional activity and thereby control cell cycle progression. γ-Tubulin contains a C-terminal signal that results in its translocation to the nucleus dur...

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Detalles Bibliográficos
Autores principales: Höög, Greta, Zarrizi, Reihaneh, von Stedingk, Kristoffer, Jonsson, Kristina, Alvarado-Kristensson, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205837/
https://www.ncbi.nlm.nih.gov/pubmed/21788450
http://dx.doi.org/10.1096/fj.11-187484