Crystal Structure of the Complex mAb 17.2 and the C-Terminal Region of Trypanosoma cruzi P2β Protein: Implications in Cross-Reactivity

Patients with Chronic Chagas' Heart Disease possess high levels of antibodies against the carboxyl-terminal end of the ribosomal P2ß protein of Trypanosoma cruzi (TcP2ß). These antibodies, as well as the murine monoclonal antibody (mAb) 17.2, recognize the last 13 amino acids of TcP2ß (called t...

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Detalles Bibliográficos
Autores principales: Pizarro, Juan Carlos, Boulot, Ginette, Bentley, Graham A., Gómez, Karina A., Hoebeke, Johan, Hontebeyrie, Mireille, Levin, Mariano J., Smulski, Cristian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206007/
https://www.ncbi.nlm.nih.gov/pubmed/22069505
http://dx.doi.org/10.1371/journal.pntd.0001375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206007/
https://www.ncbi.nlm.nih.gov/pubmed/22069505
http://dx.doi.org/10.1371/journal.pntd.0001375

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