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Cell-Associated Flagella Enhance the Protection Conferred by Mucosally-Administered Attenuated Salmonella Paratyphi A Vaccines

BACKGROUND: Antibiotic-resistant Salmonella enterica serovar Paratyphi A, the agent of paratyphoid A fever, poses an emerging public health dilemma in endemic areas of Asia and among travelers, as there is no licensed vaccine. Integral to our efforts to develop a S. Paratyphi A vaccine, we addressed...

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Detalles Bibliográficos
Autores principales: Gat, Orit, Galen, James E., Tennant, Sharon, Simon, Raphael, Blackwelder, William C., Silverman, David J., Pasetti, Marcela F., Levine, Myron M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206010/
https://www.ncbi.nlm.nih.gov/pubmed/22069504
http://dx.doi.org/10.1371/journal.pntd.0001373