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Platelets Retain High Levels of Active Plasminogen Activator Inhibitor 1

The vascular fibrinolytic system is crucial for spontaneous lysis of blood clots. Plasminogen activator inhibitor 1 (PAI-1), the principal inhibitor of the key fibrinolytic enzyme tissue-type plasminogen activator (tPA), is present in platelets at high concentrations. However, the majority of PAI-1...

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Detalles Bibliográficos
Autores principales: Brogren, Helén, Wallmark, Karin, Deinum, Johanna, Karlsson, Lena, Jern, Sverker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206048/
https://www.ncbi.nlm.nih.gov/pubmed/22069469
http://dx.doi.org/10.1371/journal.pone.0026762