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Platelets Retain High Levels of Active Plasminogen Activator Inhibitor 1
The vascular fibrinolytic system is crucial for spontaneous lysis of blood clots. Plasminogen activator inhibitor 1 (PAI-1), the principal inhibitor of the key fibrinolytic enzyme tissue-type plasminogen activator (tPA), is present in platelets at high concentrations. However, the majority of PAI-1...
Autores principales: | Brogren, Helén, Wallmark, Karin, Deinum, Johanna, Karlsson, Lena, Jern, Sverker |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206048/ https://www.ncbi.nlm.nih.gov/pubmed/22069469 http://dx.doi.org/10.1371/journal.pone.0026762 |
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