An Inducible Cell-Cell Fusion System with Integrated Ability to Measure the Efficiency and Specificity of HIV-1 Entry Inhibitors

HIV-1 envelope glycoproteins (Envs) mediate virus entry by fusing the viral and target cell membranes, a multi-step process that represents an attractive target for inhibition. Entry inhibitors with broad-range activity against diverse isolates of HIV-1 may be extremely useful as lead compounds for...

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Detalles Bibliográficos
Autores principales: Herschhorn, Alon, Finzi, Andres, Jones, David M., Courter, Joel R., Sugawara, Akihiro, Smith, Amos B., Sodroski, Joseph G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206054/
https://www.ncbi.nlm.nih.gov/pubmed/22069466
http://dx.doi.org/10.1371/journal.pone.0026731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206054/
https://www.ncbi.nlm.nih.gov/pubmed/22069466
http://dx.doi.org/10.1371/journal.pone.0026731

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