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The Molecular Basis for the Broad Substrate Specificity of Human Sulfotransferase 1A1

Cytosolic sulfotransferases (SULTs) are mammalian enzymes that detoxify a wide variety of chemicals through the addition of a sulfate group. Despite extensive research, the molecular basis for the broad specificity of SULTs is still not understood. Here, structural, protein engineering and kinetic a...

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Detalles Bibliográficos
Autores principales: Berger, Ilana, Guttman, Chen, Amar, Dotan, Zarivach, Raz, Aharoni, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206062/
https://www.ncbi.nlm.nih.gov/pubmed/22069470
http://dx.doi.org/10.1371/journal.pone.0026794