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CD44 Upregulation in E-Cadherin-Negative Esophageal Cancers Results in Cell Invasion

E-cadherin is frequently lost during epithelial-mesenchymal transition and the progression of epithelial tumorigenesis. We found a marker of epithelial-mesenchymal transition, CD44, upregulated in response to functional loss of E-cadherin in esophageal cell lines and cancer. Loss of E-cadherin expre...

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Detalles Bibliográficos
Autores principales: Le Bras, Grégoire F., Allison, Gillian L., Richards, Nicole F., Ansari, Shazia S., Washington, M. Kay, Andl, Claudia D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206075/
https://www.ncbi.nlm.nih.gov/pubmed/22069487
http://dx.doi.org/10.1371/journal.pone.0027063