Cargando…

Overexpression of scavenger receptor LOX-1 in endothelial cells promotes atherogenesis in the ApoE(−/−) mouse model

AIMS: The oxidized low-density lipoprotein receptor LOX-1 is up-regulated on activated endothelial cells, for example, the endothelium of atherosclerosis-prone sites, in both human and animal models. We examined whether endothelial LOX-1 overexpression may contribute to atherogenesis. METHODS: Adeno...

Descripción completa

Detalles Bibliográficos
Autores principales: White, Stephen J., Sala-Newby, Graciela B., Newby, Andrew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Pub. Co 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206208/
https://www.ncbi.nlm.nih.gov/pubmed/20943418
http://dx.doi.org/10.1016/j.carpath.2010.08.007