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Overexpression of scavenger receptor LOX-1 in endothelial cells promotes atherogenesis in the ApoE(−/−) mouse model
AIMS: The oxidized low-density lipoprotein receptor LOX-1 is up-regulated on activated endothelial cells, for example, the endothelium of atherosclerosis-prone sites, in both human and animal models. We examined whether endothelial LOX-1 overexpression may contribute to atherogenesis. METHODS: Adeno...
Autores principales: | White, Stephen J., Sala-Newby, Graciela B., Newby, Andrew C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science Pub. Co
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206208/ https://www.ncbi.nlm.nih.gov/pubmed/20943418 http://dx.doi.org/10.1016/j.carpath.2010.08.007 |
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