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Structural basis for the channel function of a degraded ABC transporter, CFTR (ABCC7)

Cystic fibrosis transmembrane conductance regulator (CFTR) is a member of the ATP-binding cassette (ABC) transporter superfamily, but little is known about how this ion channel that harbors an uninterrupted ion permeation pathway evolves from a transporter that works by alternately exposing its subs...

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Detalles Bibliográficos
Autores principales: Bai, Yonghong, Li, Min, Hwang, Tzyh-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206304/
https://www.ncbi.nlm.nih.gov/pubmed/22042986
http://dx.doi.org/10.1085/jgp.201110705