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Molecular dynamics simulations of the Cx26 hemichannel: Evaluation of structural models with Brownian dynamics

The recently published crystal structure of the Cx26 gap junction channel provides a unique opportunity for elucidation of the structure of the conductive connexin pore and the molecular determinants of its ion permeation properties (conductance, current–voltage [I-V] relations, and charge selectivi...

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Detalles Bibliográficos
Autores principales: Kwon, Taekyung, Harris, Andrew L., Rossi, Angelo, Bargiello, Thaddeus A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206306/
https://www.ncbi.nlm.nih.gov/pubmed/22006989
http://dx.doi.org/10.1085/jgp.201110679