Influence of pH on Ca(2+) current and its control of electrical and Ca(2+) signaling in ventricular myocytes

Modulation of L-type Ca(2+) current (I(Ca,L)) by H(+) ions in cardiac myocytes is controversial, with widely discrepant responses reported. The pH sensitivity of I(Ca,L) was investigated (whole cell voltage clamp) while measuring intracellular Ca(2+) (Ca(2+)(i)) or pH(i) (epifluorescence microscopy)...

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Detalles Bibliográficos
Autores principales: Saegusa, Noriko, Moorhouse, Emma, Vaughan-Jones, Richard D., Spitzer, Kenneth W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206307/
https://www.ncbi.nlm.nih.gov/pubmed/22042988
http://dx.doi.org/10.1085/jgp.201110658

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206307/
https://www.ncbi.nlm.nih.gov/pubmed/22042988
http://dx.doi.org/10.1085/jgp.201110658

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