A coding-independent function of gene and pseudogene mRNAs regulates tumour biology

The canonical role of messenger RNA (mRNA) is to deliver protein-coding information to sites of protein synthesis. However, given that microRNAs bind to RNAs, we hypothesized that RNAs possess a biological role in cancer cells that relies upon their ability to compete for microRNA binding and is ind...

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Detalles Bibliográficos
Autores principales: Poliseno, Laura, Salmena, Leonardo, Zhang, Jiangwen, Carver, Brett, Haveman, William J., Pandolfi, Pier Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206313/
https://www.ncbi.nlm.nih.gov/pubmed/20577206
http://dx.doi.org/10.1038/nature09144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206313/
https://www.ncbi.nlm.nih.gov/pubmed/20577206
http://dx.doi.org/10.1038/nature09144

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