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Phosphorylation at serine 331 is required for Aurora B activation

Aurora B kinase activity is required for successful cell division. In this paper, we show that Aurora B is phosphorylated at serine 331 (Ser331) during mitosis and that phosphorylated Aurora B localizes to kinetochores in prometaphase cells. Chk1 kinase is essential for Ser331 phosphorylation during...

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Detalles Bibliográficos
Autores principales: Petsalaki, Eleni, Akoumianaki, Tonia, Black, Elizabeth J., Gillespie, David A.F., Zachos, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206340/
https://www.ncbi.nlm.nih.gov/pubmed/22024163
http://dx.doi.org/10.1083/jcb.201104023