Multiple pathways can bypass the essential role of fission yeast Hsk1 kinase in DNA replication initiation

Cdc7/Hsk1 is a conserved kinase required for initiation of DNA replication that potentially regulates timing and locations of replication origin firing. Here, we show that viability of fission yeast hsk1Δ cells can be restored by loss of mrc1, which is required for maintenance of replication fork in...

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Detalles Bibliográficos
Autores principales: Matsumoto, Seiji, Hayano, Motoshi, Kanoh, Yutaka, Masai, Hisao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206344/
https://www.ncbi.nlm.nih.gov/pubmed/22024164
http://dx.doi.org/10.1083/jcb.201107025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206344/
https://www.ncbi.nlm.nih.gov/pubmed/22024164
http://dx.doi.org/10.1083/jcb.201107025

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