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Multiple pathways can bypass the essential role of fission yeast Hsk1 kinase in DNA replication initiation
Cdc7/Hsk1 is a conserved kinase required for initiation of DNA replication that potentially regulates timing and locations of replication origin firing. Here, we show that viability of fission yeast hsk1Δ cells can be restored by loss of mrc1, which is required for maintenance of replication fork in...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206344/ https://www.ncbi.nlm.nih.gov/pubmed/22024164 http://dx.doi.org/10.1083/jcb.201107025 |