Selective repression of MEF2 activity by PKA-dependent proteolysis of HDAC4

Histone deacetylase 4 (HDAC4) regulates numerous gene expression programs through its signal-dependent repression of myocyte enhancer factor 2 (MEF2) and serum response factor (SRF) transcription factors. In cardiomyocytes, calcium/calmodulin-dependent protein kinase II (CaMKII) signaling promotes h...

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Detalles Bibliográficos
Autores principales: Backs, Johannes, Worst, Barbara C., Lehmann, Lorenz H., Patrick, David M., Jebessa, Zegeye, Kreusser, Michael M., Sun, Qiang, Chen, Lan, Heft, Claudia, Katus, Hugo A., Olson, Eric N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206346/
https://www.ncbi.nlm.nih.gov/pubmed/22042619
http://dx.doi.org/10.1083/jcb.201105063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206346/
https://www.ncbi.nlm.nih.gov/pubmed/22042619
http://dx.doi.org/10.1083/jcb.201105063

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