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Drosophila ATM and ATR have distinct activities in the regulation of meiotic DNA damage and repair

Ataxia telangiectasia–mutated (ATM) and ataxia telangiectasia–related (ATR) kinases are conserved regulators of cellular responses to double strand breaks (DSBs). During meiosis, however, the functions of these kinases in DSB repair and the deoxyribonucleic acid (DNA) damage checkpoint are unclear....

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Detalles Bibliográficos
Autores principales: Joyce, Eric F., Pedersen, Michael, Tiong, Stanley, White-Brown, Sanese K., Paul, Anshu, Campbell, Shelagh D., McKim, Kim S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206348/
https://www.ncbi.nlm.nih.gov/pubmed/22024169
http://dx.doi.org/10.1083/jcb.201104121