Actin filament severing by cofilin is more important for assembly than constriction of the cytokinetic contractile ring

We created two new mutants of fission yeast cofilin to investigate why cytokinesis in many organisms depends on this small actin-binding protein. These mutant cofilins bound actin monomers normally, but bound and severed ADP-actin filaments much slower than wild-type cofilin. Cells depending on muta...

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Detalles Bibliográficos
Autores principales: Chen, Qian, Pollard, Thomas D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206353/
https://www.ncbi.nlm.nih.gov/pubmed/22024167
http://dx.doi.org/10.1083/jcb.201103067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206353/
https://www.ncbi.nlm.nih.gov/pubmed/22024167
http://dx.doi.org/10.1083/jcb.201103067

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