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Actin filament severing by cofilin is more important for assembly than constriction of the cytokinetic contractile ring
We created two new mutants of fission yeast cofilin to investigate why cytokinesis in many organisms depends on this small actin-binding protein. These mutant cofilins bound actin monomers normally, but bound and severed ADP-actin filaments much slower than wild-type cofilin. Cells depending on muta...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206353/ https://www.ncbi.nlm.nih.gov/pubmed/22024167 http://dx.doi.org/10.1083/jcb.201103067 |