Discovery of potent, novel, non-toxic anti-malarial compounds via quantum modelling, virtual screening and in vitro experimental validation

BACKGROUND: Developing resistance towards existing anti-malarial therapies emphasize the urgent need for new therapeutic options. Additionally, many malaria drugs in use today have high toxicity and low therapeutic indices. Gradient Biomodeling, LLC has developed a quantum-model search technology th...

Descripción completa

Detalles Bibliográficos
Autores principales: Sullivan, David J, Kaludov, Nikola, Martinov, Martin N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206494/
https://www.ncbi.nlm.nih.gov/pubmed/21933377
http://dx.doi.org/10.1186/1475-2875-10-274

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206494/
https://www.ncbi.nlm.nih.gov/pubmed/21933377
http://dx.doi.org/10.1186/1475-2875-10-274

Ejemplares similares