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Discovery of potent, novel, non-toxic anti-malarial compounds via quantum modelling, virtual screening and in vitro experimental validation

BACKGROUND: Developing resistance towards existing anti-malarial therapies emphasize the urgent need for new therapeutic options. Additionally, many malaria drugs in use today have high toxicity and low therapeutic indices. Gradient Biomodeling, LLC has developed a quantum-model search technology th...

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Detalles Bibliográficos
Autores principales:	Sullivan, David J, Kaludov, Nikola, Martinov, Martin N
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206494/ https://www.ncbi.nlm.nih.gov/pubmed/21933377 http://dx.doi.org/10.1186/1475-2875-10-274

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