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Neurosteroid Binding Sites on the GABA(A) Receptor Complex as Novel Targets for Therapeutics to Reduce Alcohol Abuse and Dependence

Despite the prevalence of alcohol abuse and dependence in the US and Europe, there are only five approved pharmacotherapies for alcohol dependence. Moreover, these pharmacotherapeutic options have limited clinical utility. The purpose of this paper is to present pertinent literature suggesting that...

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Detalles Bibliográficos
Autores principales: Hulin, Mary W., Amato, Russell J., Porter, Johnny R., Filipeanu, Catalin M., Winsauer, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206502/
https://www.ncbi.nlm.nih.gov/pubmed/22110489
http://dx.doi.org/10.1155/2011/926361