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Severe congenital neutropenia, a genetically heterogeneous disease group with an increased risk of AML/MDS
Over the past decade, enormous progress has been made in the understanding of severe congenital neutropenia (SCN), by identification of several causal gene mutations: in ELANE, GFI1, HAX1, WAS and G3PC3. SCN is a preleukemic condition, independent of the genetic subtype. Acquired CSF3R mutations are...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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PAGEPress Publications
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206537/ https://www.ncbi.nlm.nih.gov/pubmed/22053285 http://dx.doi.org/10.4081/pr.2011.s2.e9 |