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Severe congenital neutropenia, a genetically heterogeneous disease group with an increased risk of AML/MDS

Over the past decade, enormous progress has been made in the understanding of severe congenital neutropenia (SCN), by identification of several causal gene mutations: in ELANE, GFI1, HAX1, WAS and G3PC3. SCN is a preleukemic condition, independent of the genetic subtype. Acquired CSF3R mutations are...

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Detalles Bibliográficos
Autores principales: Vandenberghe, Peter, Beel, Karolien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206537/
https://www.ncbi.nlm.nih.gov/pubmed/22053285
http://dx.doi.org/10.4081/pr.2011.s2.e9