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PP2A Inhibition Assay Using Recombinant Enzyme for Rapid Detection of Okadaic Acid and Its Analogs in Shellfish

Okadaic acid and its analogs (OAs) responsible for diarrhetic shellfish poisoning (DSP) strongly inhibit protein phosphatase 2A (PP2A) and thus are quantifiable by measuring the extent of the enzyme inhibition. In this study, we evaluated the suitability of the catalytic subunit of recombinant human...

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Detalles Bibliográficos
Autores principales: Ikehara, Tsuyoshi, Imamura, Shihoko, Yoshino, Atsushi, Yasumoto, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206612/
https://www.ncbi.nlm.nih.gov/pubmed/22069554
http://dx.doi.org/10.3390/toxins2010195