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Calprotectin (S100A8/S100A9) and Myeloperoxidase: Co-Regulators of Formation of Reactive Oxygen Species

Inflammatory mediators trigger polymorphonuclear neutrophils (PMN) to produce reactive oxygen species (ROS: O(2)(-), H(2)O(2), ∙OH). Mediated by myeloperoxidase in PMN, HOCl is formed, detectable in a chemiluminescence (CL) assay. We have shown that the abundant cytosolic PMN protein calprotectin (S...

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Detalles Bibliográficos
Autores principales: Bøyum, Arne, Skrede, Knut Kristian, Myhre, Oddvar, Tennfjord, Vivi-Ann, Neurauter, Christine Gran, Tolleshaug, Helge, Knudsen, Eirunn, Opstad, Per Kristian, Bjørås, Magnar, Benestad, Haakon B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206613/
https://www.ncbi.nlm.nih.gov/pubmed/22069549
http://dx.doi.org/10.3390/toxins2010095