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Cytotoxic Necrotizing Factors (CNFs)−A Growing Toxin Family

The Escherichia coli Cytotoxic Necrotizing Factors, CNF1, CNF2, CNF3 and CNFY from Yersinia pseudotuberculosis belong to a family of deamidating toxins. CNFs deamidate glutamine 63/61 in the switch II region of Rho GTPases that is essential for GTP hydrolysing activity. Deamidation leads to constitu...

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Detalles Bibliográficos
Autores principales: Knust, Zeynep, Schmidt, Gudula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206620/
https://www.ncbi.nlm.nih.gov/pubmed/22069550
http://dx.doi.org/10.3390/toxins2010116