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Protein Domain Analysis of C. botulinum Type A Neurotoxin and Its Relationship with Other Botulinum Serotypes

Botulinum neurotoxins (BoNTs) are highly potent poisons produced by seven serotypes of Clostridium botulinum. The mechanism of neurotoxin action is a multistep process which leads to the cleavage of one of three different SNARE proteins essential for synaptic vesicle fusion and transmission of the n...

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Detalles Bibliográficos
Autores principales: Sharma, Shashi K., Basavanna, Uma, Shukla, Hem D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206622/
https://www.ncbi.nlm.nih.gov/pubmed/22069543
http://dx.doi.org/10.3390/toxins2010001