PDZ binding of TARP©-8 controls synaptic transmission, but not synaptic plasticity

Reduction in synaptic transmission and plasticity in mice lacking the hippocampus-enriched AMPAR auxiliary subunit, TARP©-8, could be due to reduction in AMPAR expression or a direct role of ©-8. Here, we generated TARP©-8Δ4 knock-in mice lacking the C-terminal PDZ ligand. We found that synaptic tra...

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Detalles Bibliográficos
Autores principales: Sumioka, Akio, Brown, Travis, Kato, Akihiko, Bredt, David S., Kauer, Julie A., Tomita, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206644/
https://www.ncbi.nlm.nih.gov/pubmed/22002768
http://dx.doi.org/10.1038/nn.2952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206644/
https://www.ncbi.nlm.nih.gov/pubmed/22002768
http://dx.doi.org/10.1038/nn.2952

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