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Multiple Phenotypes Resulting from a Mutagenesis Screen for Pharynx Muscle Mutations in Caenorhabditis elegans

We describe a novel screen to isolate pharyngeal cell morphology mutants in Caenorhabditis elegans using myo-2::GFP to rapidly identify abnormally shaped pharynxes in EMS (Ethyl Methanesulfonate) mutagenized worms. We observed over 83 C. elegans lines with distinctive pharyngeal phenotypes in worms...

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Detalles Bibliográficos
Autores principales: Ferrier, Andrew, Charron, Alexandra, Sadozai, Yama, Switaj, Lynn, Szutenbach, Anneliese, Smith, Pliny A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206800/
https://www.ncbi.nlm.nih.gov/pubmed/22073173
http://dx.doi.org/10.1371/journal.pone.0026594