A Novel Dimer-Tetramer Transition Captured by the Crystal Structure of the HIV-1 Nef

HIV-1 Nef modulates disease progression through interactions with over 30 host proteins. Individual chains fold into membrane-interacting N-terminal and C-terminal core (Nef(core)) domains respectively. Nef exists as small oligomers near membranes and associates into higher oligomers such as tetrame...

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Detalles Bibliográficos
Autores principales: Singh, Pankaj, Yadav, Gaya Prasad, Gupta, Sudeepti, Tripathi, Anil Kumar, Ramachandran, Ravishankar, Tripathi, Raj Kamal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206816/
https://www.ncbi.nlm.nih.gov/pubmed/22073177
http://dx.doi.org/10.1371/journal.pone.0026629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206816/
https://www.ncbi.nlm.nih.gov/pubmed/22073177
http://dx.doi.org/10.1371/journal.pone.0026629

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