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PLGA, PLGA-TMC and TMC-TPP Nanoparticles Differentially Modulate the Outcome of Nasal Vaccination by Inducing Tolerance or Enhancing Humoral Immunity

Development of vaccines in autoimmune diseases has received wide attention over the last decade. However, many vaccines showed limited clinical efficacy. To enhance vaccine efficacy in infectious diseases, biocompatible and biodegradable polymeric nanoparticles have gained interest as antigen delive...

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Detalles Bibliográficos
Autores principales: Keijzer, Chantal, Slütter, Bram, van der Zee, Ruurd, Jiskoot, Wim, van Eden, Willem, Broere, Femke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206834/
https://www.ncbi.nlm.nih.gov/pubmed/22073184
http://dx.doi.org/10.1371/journal.pone.0026684